Restricted Research - Award List, Note/Discussion Page

Fiscal Year: 2021

259  University of North Texas  (84555)

Principal Investigator: Alonso,Ana Paula

Total Amount of Contract, Award, or Gift (Annual before 2011): $ 500,000

Exceeds $250,000 (Is it flagged?): Yes

Start and End Dates: - 1/14/24

Restricted Research: YES

Academic Discipline: Biological Sciences

Department, Center, School, or Institute: College of Science

Title of Contract, Award, or Gift: Mapping the pathways leading to industrially relevant fatty acids in Physaria fendleri

Name of Granting or Contracting Agency/Entity: U.S. Department of Agriculture

CFDA: 10.310

Program Title: N/A


1.1.1 (SAM); The goal of the proposed research is to design an effective strategy for improving hydroxy-fatty acid (HFA) production by Physaria fendleri. Physaria is a Brassicacea that produces a type of oil, naturally rich in HFAs, that is suitable for industrial applications. However, for this plant to be economically viable, its seed oil content must be improved. Our preliminary studies demonstrated that Physaria embryos metabolize carbon into biomass with an efficiency significantly lower that other photosynthesic embryos. Interestingly, Physaria use non-conventional metabolic pathways to channel carbon into oil. We hypothesize that: i) seeds with contrasting oil content result from a natural variation in gene expression and metabolism; ii) Physaria accessions accumulating more oil convert resources into biomass more efficiently, and iii) increase the flow of carbon through non-conventional pathways. We propose to use a multi-omics approach to test these hypotheses. The objectives are two-fold: 1) Identify candidate genes and metabolites associated with oil content in Physaria, and 2) Validate targets to increase oil. We anticipate that our unique strategy combining metabolomics, transcriptomic with in vivo fluxes of carbon will identify and validate novel targets to improve oil quantity in Physaria. This proposal includes activities uniquely aligned with the objectives of the Plant Health and Production and Plant Products program, specifically of the priority area

Discussion: No discussion notes


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