Restricted Research - Award List, Note/Discussion Page

Fiscal Year: 2021

256  University of North Texas  (84552)

Principal Investigator: Skellam,Elizabeth Julia

Total Amount of Contract, Award, or Gift (Annual before 2011): $ 10,000

Exceeds $250,000 (Is it flagged?): No

Start and End Dates: - 1/21/22

Restricted Research: YES

Academic Discipline: Chemistry

Department, Center, School, or Institute: College of Science

Title of Contract, Award, or Gift: Grants4Ag

Name of Granting or Contracting Agency/Entity: Bayer AG


Program Title: N/A


The proposal seeks to investigate a biocontrol agent to protect against mycotoxins. The research plan will 1) Sequence and annotate S. zeae’s genome; 2) Identify and classify all secondary metabolite biosynthetic gene clusters; 3) Develop a transformation protocol for S. zeae; 4) Elucidate the biosynthesis of pyrrocidines A/B via gene knock-out / heterologous expression; 5) Obtain transcriptome of A. zeae when inhabiting maize and its pathogens; 6) Characterize all other metabolites via heterologous expression / transcription factor over-expression; 7) Evaluate toxicity of identified metabolites.

Discussion: No discussion notes


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