Restricted Research - Award List, Note/Discussion Page

Fiscal Year: 2021

11  Texas A&M University-Kingsville  (84305)

Principal Investigator: Suntravat, M.

Total Amount of Contract, Award, or Gift (Annual before 2011): $ 693,104

Exceeds $250,000 (Is it flagged?): Yes

Start and End Dates: 4/1/20 - 3/31/23

Restricted Research: YES

Academic Discipline: National Natural Toxins Research Center

Department, Center, School, or Institute: Arts & Sciences

Title of Contract, Award, or Gift: The acute effects of snake venom CRiSP toxins on blood and lymphatic endothelial cell permeability: new insights into the pathophysiology of snakebite

Name of Granting or Contracting Agency/Entity: National Institutes of Health (NIH)

Program Title: none
CFDA Linked: Blood Diseases and Resources Research


Continuation of previously approved # 81498. SAMS 1.1.1.- The goal of this study is to investigate the role that a specific family of snake venom toxins, the Cysteine-Rick Secretory Proteins (svCRiSPs) plays in snakebite, focusing specifically on the effects of these toxins on the function of the blood and lymphatic vessels located in proximity to the bite. Knowledge gained from these studies will provide insights into the molecular mechanisms that underlie the effects of svCRiSPs on vascular function and will contribute to our understanding of the pathophysiology of snakebite.

Discussion: No discussion notes


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